Cnidicin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Cnidicin 具有抗过敏和抗炎活性，抑制 RAW 264.7 细胞中肥大细胞脱颗粒和 NO 生成（IC50 值，7.5 microM）。

Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM). Cnidicin exhibits a significant inhibition on the proliferation of cultured human tumor cells such as A549 (non small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nervous system) and HCT-15 (colon) in vitro .

Cnidicin shows a significant inhibition upon the release of beta-hexosaminidase from the cultured RBL-2H3 cells in a dose dependent manner (IC50= 25 μM) and upon the nitric oxide production from the activated RAW264.7 cells (IC50=7.5 μM).

——

——

Immunology/Inflammation

NOS

NO Synthase|NOS

——

——

14348-21-1

354.4

C21H22O5

>98% (HPLC)

DMSO:10 mM

CC(=CCOC1=C2C=COC2=C(C3=C1C=CC(=O)O3)OCC=C(C)C)C

——

(-20℃)

With Ice Pack

≥ 2 years