021-51111890
购物车（）
sales@molnova.cn
Mutant IDH1 inhibitor
CAS No. 1429180-08-4
Mutant IDH1 inhibitor ( —— )
产品货号. M23590 CAS No. 1429180-08-4
Mutant IDH1抑制剂是突变IDH1 R132H的有效抑制剂（IC50：< 72 nM）。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥752 | 有现货 |
|
| 10MG | ￥1321 | 有现货 |
|
| 25MG | ￥2158 | 有现货 |
|
| 50MG | ￥3097 | 有现货 |
|
| 100MG | ￥4077 | 有现货 |
|
| 200MG | ￥5337 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥775 | 有现货 |
|
生物学信息
-
产品名称Mutant IDH1 inhibitor
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Mutant IDH1抑制剂是突变IDH1 R132H的有效抑制剂（IC50：< 72 nM）。
-
产品描述Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).
-
体外实验Mutant IDH1 inhibitor is a potent IDH1 R132H inhibitor, and used for the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer.
-
体内实验——
-
同义词——
-
通路Metabolic Enzyme/Protease
-
靶点Dehydrogenase
-
受体mutant IDH1 R132H
-
研究领域——
-
适应症——
化学信息
-
CAS Number1429180-08-4
-
分子量466.58
-
分子式C25H34N6O3
-
纯度>98% (HPLC)
-
溶解度DMSO:30 mg/mL (64.3 mM)
-
SMILESCC(C)[C@@H](COC1=O)N1c1nc(N[C@@H](C)c2ccc(CN(CC3)CCN3C(C)=O)cc2)ncc1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.3-Pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH and their preparation. Patent WO 2013046136 A1 20130404
产品手册
关联产品
-
Manitimus
Manitimus 是一种 dehydroorotate dehydrogenase 的抑制剂，同时为有效的免疫抑制药。Manitimus 是一种点击化学试剂。它含有 Alkyne 基团，可以和含有 Azide 基团的分子发生铜催化的叠氮-炔环加成反应 (CuAAc)。
-
DSM421
DSM421 (DSM-421) is a dihydrodehydrogenase inhibitor (DHODH) that is in preclinical development as a potential treatment option for malaria and has shown activity against field isolates of both P. falciparum and P. vivax.
-
CB29
CB29 is a specific inhibitor of aldehyde dehydrogenase 3A1 (ALDH3A1).
