Mutated EGFR-IN-1
CAS No. 1421372-66-8
Mutated EGFR-IN-1 ( Osimertinib analog )
产品货号. M23574 CAS No. 1421372-66-8
突变EGFR-IN-1是突变EGFR抑制剂设计的有用中间体,例如L858R EGFR、Exon19缺失激活突变体和T790M抗性突变体。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ¥107 | 有现货 |
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| 5MG | ¥155 | 有现货 |
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| 10MG | ¥235 | 有现货 |
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| 25MG | ¥368 | 有现货 |
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| 50MG | ¥483 | 有现货 |
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| 100MG | ¥655 | 有现货 |
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| 500MG | ¥1728 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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| 1 mL x 10 mM in DMSO | ¥212 | 有现货 |
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生物学信息
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产品名称Mutated EGFR-IN-1
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述突变EGFR-IN-1是突变EGFR抑制剂设计的有用中间体,例如L858R EGFR、Exon19缺失激活突变体和T790M抗性突变体。
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产品描述Mutated EGFR-IN-1 is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant, and T790M resistance mutant.
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体外实验——
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体内实验——
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同义词Osimertinib analog
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通路Angiogenesis
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靶点EGFR
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受体EGFR (L858R)|EGFR (T790M)|EGFR(Exon 19 deletion/T790M)
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研究领域——
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适应症——
化学信息
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CAS Number1421372-66-8
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分子量445.56
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分子式C25H31N7O
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纯度>98% (HPLC)
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溶解度DMSO: 75 mg/mL (168.33 mM)
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SMILESNC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C)C)C
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Patent WO 2013014448 A2 - (2, 4, 5 - substituted -anilino) pyrimidine derivatives as egfr modulators useful for treating cancer .
产品手册
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