NVP-CGM097
CAS No. 1313363-54-0
NVP-CGM097 ( CGM097 )
产品货号. M23472 CAS No. 1313363-54-0
NVP-CGM097 是一种有效且特异性的 MDM2 抑制剂(对于 hMDM2,IC50:1.7 nM)。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ¥660 | 有现货 |
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| 5MG | ¥1254 | 有现货 |
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| 10MG | ¥2119 | 有现货 |
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| 25MG | ¥3469 | 有现货 |
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| 50MG | ¥4920 | 有现货 |
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| 100MG | ¥6552 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ¥1824 | 有现货 |
|
生物学信息
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产品名称NVP-CGM097
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述NVP-CGM097 是一种有效且特异性的 MDM2 抑制剂(对于 hMDM2,IC50:1.7 nM)。
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产品描述NVP-CGM097 is an effective and specific MDM2 inhibitor (IC50: 1.7 nM for hMDM2).
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体外实验——
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体内实验——
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同义词CGM097
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通路Others
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靶点Other Targets
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受体E1/E2/E3 Enzyme|MDM2
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研究领域——
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适应症——
化学信息
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CAS Number1313363-54-0
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分子量659.26
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分子式C38H47ClN4O4
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纯度>98% (HPLC)
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溶解度DMSO:48 mg/mL (72.81 mM);Water:Insoluble
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SMILESO=C1N(C2=CC=C(N(C)C[C@H]3CC[C@H](N4CC(N(C)CC4)=O)CC3)C=C2)[C@@H](C5=CC=C(Cl)C=C5)C6=C(C=C(OC)C(OC(C)C)=C6)C1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Holzer P, et al. Discovery of a Dihydroisoquinolinone Derivative (NVP-CGM097): A Highly Potent and Selective MDM2 Inhibitor Undergoing Phase 1 Clinical Trials in p53wt Tumors. J Med Chem. 2015 Aug 27;58(16):6348-58
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