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Decursinol angelate
CAS No. 130848-06-5
Decursinol angelate ( —— )
产品货号. M23465 CAS No. 130848-06-5
Decursinol Angelate 具有抗肿瘤、抗炎、抗氧化和保肝活性，它通过抑制 VEGFR-2 信号通路来抑制 VEGF 诱导的血管生成。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥414 | 有现货 |
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| 10MG | ￥616 | 有现货 |
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| 25MG | ￥1097 | 有现货 |
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| 50MG | ￥1646 | 有现货 |
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| 100MG | ￥2349 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥463 | 有现货 |
|
生物学信息
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产品名称Decursinol angelate
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Decursinol Angelate 具有抗肿瘤、抗炎、抗氧化和保肝活性，它通过抑制 VEGFR-2 信号通路来抑制 VEGF 诱导的血管生成。
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产品描述Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway; it also suppresses invasion and inflammatory activation of cancer cells through modulation of PI3K/AKT, ERK and NF-kappaB, its anti-inflammatory activity may contribute to its anti-cancer activity.
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体外实验——
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体内实验——
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同义词——
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通路MAPK/ERK Signaling
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靶点ERK
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受体ERK|JNK|PKC|VEGFR
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研究领域——
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适应症——
化学信息
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CAS Number130848-06-5
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分子量328.36
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分子式C19H20O5
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纯度>98% (HPLC)
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溶解度DMSO:65 mg/mL (197.95 mM)
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SMILESC/C=C(C)\C(O[C@H]1CC(C=C(C=CC(O2)=O)C2=C3)=C3OC1(C)C)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Decursin and decursinol angelate improve wound healing by upregulating transcription of genes encoding extracellular matrix remodeling proteins, inflammatory cytokines, and growth factors in human keratinocytes.Biochem Biophys Res Commun. 2018 May 23;499(4):979-984.
