BD-AcAc 2

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

在饮食中添加 BD-AcAc 2（酮酯）可使动物平均血液酮体升高 3.5 mm，并降低血浆葡萄糖、胰岛素和瘦素。

BD-AcAc 2 (Ketone Ester), added in diet, could elevate mean blood ketone bodies of 3.5 mm and lowered plasma glucose, insulin, and leptin in animals.

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(R,R)-BD-AcAc 2 (D-3HHB) increases specific muscle force, moderately raises blood glucose concentrations, lowers Aldh3b2 gene expression, increases blood Na+ levels and blood creatinine levels, and reduces plasma free fatty acid concentrations. Animal Model:Septic miceDosage:10, 20, 40 and 80 mmol/kg/dayAdministration:POResult:Increased specific muscle force as compared with placebo to 93% of healthy control levels at 40 mmol/kg/day.Resulted in moderately higher blood glucose concentrations as compared with placebo at 40 mmol/kg/day.Lowered Aldh3b2 gene expression than with placebo at 40 mmol/kg/day.Evoked a moderate further increase in blood Na+ levels and increased blood creatinine levels at 20 mmol/kg/day.Reduced plasma free fatty acid concentrations by 10 or 20 mmol/kg/day.Hepatic gene expression levels of Aldh1a7 was also reduced by sepsis but increased by D-3HHB.

Ketone Ester

Others

Other Targets

Others

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1208313-97-6

176.21

C8H16O4

>98% (HPLC)

DMSO:96 mg/mL (544.80 mM; Need ultrasonic)；H2O:30 mg/mL (170.25 mM; ultrasonic and heat to 60°C)

C[C@H](CCOC(C[C@@H](C)O)=O)O

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(-20℃)

With Ice Pack

≥ 2 years