Hydroxychloroquine ( —— )

产品货号. M23351 CAS No. 118-42-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Hydroxychloroquine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

羟氯喹 (HCQ) 是一种碱化溶酶体化合物，在体外通过诱导肾癌细胞凋亡并抑制 TLR7/9 发挥作用。
产品描述

Hydroxychloroquine (HCQ) is an alkalinizing lysosomatropic drug that acts by inducing apoptosis of renal cancer cells in vitro and inhibiting TLR7/9. It is a medication used to prevent and treat malaria, and it's also being studied as an experimental treatment for COVID-19.
体外实验

——
体内实验

——
同义词

——
通路

Immunology/Inflammation
靶点

TLR
受体

TLR7/9
研究领域

——
适应症

——

CAS Number

118-42-3
分子量

335.87
分子式

C18H26ClN3O
纯度

>98% (HPLC)
溶解度

1M HCl : 99 mg/mL (294.75 mM; adjust pH to 2 with HCl); H2O : 1.65 mg/mL (4.91 mM; ultrasonic and warming and heat to 60°C); DMSO : < 1 mg/mL (insoluble or slightly soluble)
SMILES

CCN(CCCC(C)Nc1c(ccc(Cl)c2)c2ncc1)CCO
化学全称

——

1.Ponticelli C, Moroni G. Hydroxychloroquine in systemic lupus erythematosus (SLE). Expert Opin Drug Saf. 2017 Mar;16(3):411-419.

计算器

产品手册

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