Amorolfine HCL

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

阿莫罗芬 HCL 是一种抗真菌试剂。它通过选择性地中断麦角甾醇合成途径中的两个步骤并最终破坏真菌细胞膜的功能和结构来发挥抗真菌活性。阿莫罗芬是吗啉类抗真菌药，可抑制D14还原酶和D7-D8异构酶。

Amorolfine HCL is an antifungal reagent. It exerts the antifungal activity by selectively interrupting two steps in the pathway of ergosterol synthesis and eventually disrupting the function and structure of fungal cell membrane. Amorolfine, a morpholine antifungal drug, can inhibit D14 reductase and D7-D8 isomerase. These enzymes can deplete ergosterol and cause ignosterol to accumulate in the fungal cytoplasmic cell membranes.

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GPCR/G Protein

Antibacterial

Antibiotic

Immune system/Infection

Onychomycosis

106614-68-0

354

C21H36ClNO?

>98% (HPLC)

DMSO:12.5 mg/mL (35.31 mM; Need ultrasonic);H2O:3.33 mg/mL (9.41 mM; Need ultrasonic)

CCC(C)(C)C1=CC=C(C=C1)CC(C)CN2CC(OC(C2)C)C.Cl

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(-20℃)

With Ice Pack

≥ 2 years