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Carbobenzoxyproline
CAS No. 1148-11-4
Carbobenzoxyproline ( Benzyloxycarbonylproline,Carbobenzoxy-S-proline )
产品货号. M22867 CAS No. 1148-11-4
Carbobenxyproline 是一种脯氨酸酶抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 500MG | 获取报价 | 有现货 |
|
| 1G | ￥142 | 有现货 |
|
生物学信息
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产品名称Carbobenzoxyproline
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Carbobenxyproline 是一种脯氨酸酶抑制剂。
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产品描述Carbobenzoxyproline is a prolidase inhibitor.
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体外实验Carbobenzoxyproline (6 mM; 0-10 d; pH=6.0) causes mitochondrial depolarization and increases cellular death by 33% as reported for long-term culture of fibroblasts from prolidase deficiency (PD) patients. Carbobenzoxyproline (0, 1, 3, 6 mM; 1 min; pH=6.0) results fibroblasts prolidase (FBP) hydrolysis, shows linear competitive inhibition.
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体内实验Carbobenzoxyproline (60 mg/kg; injection; once daily; 3 weeks) serves as in vivo inhibitor of erythrocytes prolidase in mice model. Animal Model:C57Bl/6J mice (4-week-old)Dosage:60 mg/kg Administration:Injection; once daily for 3 weeks Result:Resulted significant reduction of erythrocytes prolidase activity.
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同义词Benzyloxycarbonylproline,Carbobenzoxy-S-proline
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通路Others
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靶点Other Targets
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受体prolidase
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研究领域——
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适应症——
化学信息
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CAS Number1148-11-4
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分子量249.26
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分子式C13H15NO4
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纯度>98% (HPLC)
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溶解度DMSO:Soluble
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SMILESC1CC(N(C1)C(=O)OCC2=CC=CC=C2)C(=O)O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Arkadiusz, Surazynski, and, et al. Prolidase-dependent regulation of TGF c and TGF β receptor expressions in human skin fibroblasts[J]. European Journal of Pharmacology, 2010, 649(1-3):115-119.
产品手册
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