Methysticin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Methysticin 是从卡瓦根中分离出来的卡瓦内酯。 Mmethylsticin 表现出破骨细胞形成抑制活性。

Methysticin is a kavalactone isolated from the kava roots. Methylsticin exhibit osteoclast formation inhibitory activity. It inhibits activation of NF-χB in lung adenocarcinoma tissue, activates Nrf2 in neurons and astroglia, decreases peak amplitude of voltage-gated Na+ channels in hippocampal neurons, and suppresses growth of Fusarium, Trichoderma, and Colletotrichum.The kavalactones, and compositions thereof, are useful in mediating osteoclast activity, and as such, are useful in treating or preventing disease or disease symptoms mediated by osteoclast activity.

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Others

Other Targets

Others

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495-85-2

274.27

C15H14O5

>98% (HPLC)

In Vitro:?DMSO : 25 mg/mL (91.15 mM)

O=C1C=C(OC)C[C@H](/C=C/C2=CC=C(OCO3)C3=C2)O1

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(-20℃)

With Ice Pack

≥ 2 years