Compound 35

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

化合物35是埃博拉(马英加)和马尔堡(安哥拉)传染性病毒的优良抑制剂。化合物35是埃博拉(马英加)和马尔堡(安哥拉)传染性病毒的优良抑制剂。化合物 35 在血浆和肝微粒体（大鼠和人）中表现出良好的代谢稳定性，并且 32 不抑制 CYP3A4 或 CYP2C9。

Compounds 35 are superior inhibitors of Ebola (Mayinga) and Marburg (Angola) infectious viruses.Compounds 35 are superior inhibitors of Ebola (Mayinga) and Marburg (Angola) infectious viruses. Compounds 35 have shown good metabolic stability in plasma and liver microsomes (rat and human), and 32 did not inhibit CYP3A4 nor CYP2C9. These 4-(aminomethyl)benzamides are suitable for further optimization as inhibitors of filovirus entry, with potential to be developed as therapeutic agents for the treatment and control of Ebola virus infections.

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Others

Other Targets

Ebola (Mayinga)| Marburg (Angola)

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461.52

C25H30F3N3O2

>98% (HPLC)

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FC(F)(F)c2cc(ccc2N1CCC(C)CC1)NC(=O)c3ccc(cc3)CN4CCOCC4

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(-20℃)

With Ice Pack

≥ 2 years