piperacillin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

哌拉西林是一种半合成青霉素，具有广谱抗菌活性（尤其是假单胞菌菌株）。

Piperacillin is a semisynthetic penicillin with wide spectrum of antimicrobial activity(particularly pseudomonas strains.

——

Animal Model:BALB/c low inoculum model of K. pneumoniae, KEN-11 strain Dosage:100 mg/kg Administration:Intravenous injection (i.v.), 4 times a day, 5 d, in combination with Tazobactam (12.5 mg/kg, i.v., 4 times a day, 5 d)Result:Enabled all mice survived whereas all control mice died by 5 d, decreased the number of bacteria in lungs compared with control group.Observed no bacteria in the blood of most mice (except for two mice at the early phase) while bacteria were observed in the blood of control group. Observed few inflammatory cells in the alveoli whereas an influx of numerous inflammatory cells were observed in the control group.

Pipracil,Pipercillin,Pipril

GPCR/G Protein

Antibacterial

bacterial

——

——

61477-96-1

517.56

C23H27N5O7S

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (193.22 mM)

CCN4CCN(C(=O)N[C@@]([H])(C(=O)N[C@]1([H])C(=O)N2[C@]1([H])[S]C(C)(C)[C@]2([H])C(=O)O)c3ccccc3)C(=O)C4=O

——

(-20℃)

With Ice Pack

≥ 2 years