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QO-40
CAS No. 1259536-70-3
QO-40 ( —— )
产品货号. M21936 CAS No. 1259536-70-3
QO-40 是一种 KCNQ2/3 钾通道激活剂。QO-40 有效增强中国仓鼠卵巢细胞中表达的 KCNQ2/3 通道，并使半最大激活电压 (V(1/2)) 向超极化方向移动。 V(1/2) 以浓度依赖性方式负移。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥103 | 有现货 |
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| 5MG | ￥164 | 有现货 |
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| 10MG | ￥264 | 有现货 |
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| 25MG | ￥461 | 有现货 |
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| 50MG | ￥710 | 有现货 |
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| 100MG | ￥1017 | 有现货 |
|
| 200MG | ￥1494 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥199 | 有现货 |
|
生物学信息
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产品名称QO-40
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述QO-40 是一种 KCNQ2/3 钾通道激活剂。QO-40 有效增强中国仓鼠卵巢细胞中表达的 KCNQ2/3 通道，并使半最大激活电压 (V(1/2)) 向超极化方向移动。 V(1/2) 以浓度依赖性方式负移。
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产品描述QO-40 is a KCNQ2/3 potassium channels activator.QO-40 potently augmented KCNQ2/3 channels expressed in Chinese hamster ovary cells and shifted the half-maximal activation voltage (V(1/2)) in the hyperpolarizing direction.?The V(1/2) was negatively shifted in a concentration-dependent manner.?The compounds markedly slowed both KCNQ2/3 channel activation and deactivation kinetics.?
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体外实验——
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体内实验——
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同义词——
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通路Cell Cycle/DNA Damage
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靶点Potassium Channel
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受体KCNQ2/Q3 potassium channel
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研究领域——
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适应症——
化学信息
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CAS Number1259536-70-3
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分子量377.75
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分子式C18H11ClF3N3O
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纯度>98% (HPLC)
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溶解度——
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SMILESFC(F)(F)c1nn4C(=O)C=C(Nc4c1c3cccc2ccccc23)CCl
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Jia C , Qi J , Zhang F , et al. Activation of KCNQ2/3 Potassium Channels by Novel Pyrazolo[1,5-a]pyrimidin-7(4H)-One Derivatives[J]. Pharmacology, 2011, 87(5-6):297-310.
产品手册
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