Escin Iib

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Escin IIb 是从七叶树（七叶树的种子）中分离出来的，对动物的急性炎症具有积极作用。

Escin IIb, isolated from horse chestnut, the seeds of Aesculus hippocastanum L., has positive effects on acute inflammation in animals. Escin IIb showed potent protective effects against ethanol-induced gastric mucosal lesions.

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Escins Ia, Ib, IIa, and IIb (50-200 mg/kg) inhibit the increase of vascular permeability induced by both acetic acid in mice and histamine in rats. Escins Ib, IIa, and IIb (50-200 mg/kg) also inhibit that induced by serotonin in rats, but escin Ia didn't. Escins Ia, Ib, IIa, and IIb (200 mg/kg) inhibit the hind paw edema induced by carrageenin at the first phase in rats. Escin Ia (200 mg/kg) and escins Ib, IIa, and IIb (50-200 mg/kg) inhibit the scratching behavior induced by compound 48/80 in mice, but escin Ia was weakest.Escin IIb (10-50 mg/kg; p.o.) potently inhibits ethanol-induced gastric mucosal lesions. Animal Model:Male Sprague–Dawley rats (Ethanol-induced gastric mucosal lesions in rats)Dosage:P.o.Administration:10-50 mg/kg Result:Showed a potent protective effect against ethanol-induced gastric lesions in rats.

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Others

Other Targets

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158800-83-0

1101.23

C??H??O??

>98% (HPLC)

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OC[C@]12[C@](CC(C)(C)[C@@H](OC(/C(C)=C\C)=O)[C@@H]2OC(C)=O)([H])C3=CC[C@@]([C@@]4([C@@]([C@@](CO)([C@@H](O[C@H]5[C@H](O[C@H]6[C@H](O)[C@@H](O)[C@H](O)CO6)[C@@H](O)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@@H](C(O)=O)O5)CC4)C)([H])CC8)C)([H])[C@]8(C)[C@]3(C)C[C@H]1O

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(-20℃)

With Ice Pack

≥ 2 years