Taurohyodeoxycholic acid sodium salt

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

牛磺猪去氧胆酸钠盐是一种亲水性胆盐，对大鼠胆盐和胆汁脂质分泌有影响。

Taurohyodeoxycholic acid sodium salt a hydrophilic bile salt on bile salt and biliary lipid secretion in the rat.

Cell Proliferation Assay Cell Line:IEC-6 and caco-2 cells Concentration:0, 0.05, 0.50, and 1.00 mM Incubation Time:1, 2, 4 and 6 days Result:Significantly stimulated intestinal epithelial cell proliferation in a dose-dependent manner. Cell Cycle Analysis Cell Line:IEC-6 cells Concentration:0, 0.05, 0.50, and 1.00 mM Incubation Time:24 hResult:Significantly increased cells in S phase and decreased cells in G1-phase.Western Blot Analysis Cell Line:IEC-6 cells Concentration:0.5 mM Incubation Time:1 and 6 days Result:Significantly increased c-myc protein expression.

Animal Model:C57BL/6N mice, Lipopolysaccharides (HY-D1056) injection model of sepsis Dosage:0.5 mg/kg Administration:Intravenous injection, 30 min or 24 h after LPS injection Result:Improved the survival rate of mice with sepsis. Decreased liver and kidney damage in septic mice. Ameliorated systemic inflammation and normalized blood pressure in septic mice.

Taurodeoxychloic Acid sodium hydrate | Sodium taurodeoxycholate monohydrate

Apoptosis

Caspase

Caspase

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110026-03-4

540.71

C26H47NNaO7S+

>98% (HPLC)

DMSO:125 mg/mL (231.18 mM)

C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@@H]2[C@]1(CC[C@H]3[C@H]2C[C@@H]([C@H]4[C@@]3(CC[C@H](C4)O)C)O)C.[Na+]

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(-20℃)

With Ice Pack

≥ 2 years