Substance P 1-7
CAS No. 68060-49-1
Substance P 1-7 ( —— )
产品货号. M20901 CAS No. 68060-49-1
P物质1-7是速激肽P物质(SP)蛋白水解降解后形成的主要生物活性代谢产物,具有抗炎、抗伤害和抗痛觉过敏作用。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ¥644 | 有现货 |
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| 5MG | ¥920 | 有现货 |
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| 10MG | ¥1472 | 有现货 |
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| 25MG | ¥2593 | 有现货 |
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| 50MG | ¥3889 | 有现货 |
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| 100MG | ¥5646 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Substance P 1-7
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述P物质1-7是速激肽P物质(SP)蛋白水解降解后形成的主要生物活性代谢产物,具有抗炎、抗伤害和抗痛觉过敏作用。
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产品描述Substance P 1-7 is the major bioactive metabolite formed after proteolytic degradation of the tachykinin substance P (SP)with anti-inflammatory anti-nociceptive and anti-hyperalgesic effects.
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体外实验——
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体内实验Substance P (1-7) is found to act as a very potent antagonist against the SP-induced responses and is formed locally in the nigra after SP injection. It is proposed that Substance P (1-7) is an endogenous modulator of SP actions. Injection of low doses of Substance P (1-7) (1.0-4.0 pM simultaneously with SP or SP(5-11) (0.1 nM), reduce aversive behaviours induced by SP or SP(5- 11) significantly. These results indicate that SP(1-7) formed endogenously could modulate the actions of SP or SP(5-11) in the spinal cord.
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number68060-49-1
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分子量900.04
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分子式C41H65N13O10
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纯度>98% (HPLC)
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溶解度——
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SMILESN=C(N)NCCCC(N)C(=O)N1CCCC1C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)NC(CCC(N)=O)C(=O)NC(CCC(N)=O)C(=O)NC(Cc1ccccc1)C(=O)O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Herrera-Marschitz M Terenius L Sakurada T et al. The substance P(1-7) fragment is a potent modulator of substance P actions in the brain[J]. Brain Research 1990 521(1-2):316-320.
产品手册
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