NADPH tetrasodium salt

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

NADPH 四钠盐是电子受体烟酰胺腺嘌呤二核苷酸磷酸 (NADP+) 的还原形式，在各种生物反应中充当电子供体。

NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate (NADP+) and acts as an electron donor in various biological reactions.

NADPH tetrasodium salt de novo synthesis is catalyzed by NAD kinases (NADKs), which catalyze the phosphorylation of NAD+ to form NADP+. NADPH tetrasodium salt is mainly involved in catabolic reactions, whereas NADPH tetrasodium salt is primarily involved in cellular antioxidative effects and anabolic reactions. NADPH tetrasodium salt is used by glutathione reductase (GR) to reduce oxidized glutathione (GSSG) to GSH.The regeneration rate of NADPH tetrasodium salt is often the rate-limiting step for the over-production of desired chemicals, while maintaining robust cellular growth.NADPH tetrasodium salt homeostasis is regulated by varied signaling pathways and several metabolic enzymes that undergo adaptive alteration in cancer cells. The metabolic reprogramming of NADPH tetrasodium salt renders cancer cells both highly dependent on this metabolic network for antioxidant capacity and more susceptible to oxidative stress.NADPH tetrasodium salt is an essential intracellular reductant needed to eliminate lipid hydroperoxides. Indeed, NADPH tetrasodium salt levels are a biomarker of ferroptosis sensitivity across many cancer cell lines.

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Others

Other Targets

Others

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2646-71-1

833.35

C21H26N7Na4O17P3

>98% (HPLC)

H2O:35 mg/mL (42.00 mM)

[Na+].[Na+].[Na+].[Na+].NC(=O)C1=CN(C=CC1)C1OC(COP([O-])(=O)OP([O-])(=O)OCC2OC(C(OP([O-])([O-])=O)C2O)n2cnc3c(N)ncnc23)C(O)C1O

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(-20℃)

With Ice Pack

≥ 2 years