ML367 ( —— )

产品货号. M20178 CAS No. 381168-77-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

ML367
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

ML367 是 ATPase 家族 AAA 结构域蛋白 5 (ATAD5) 稳定性的有效抑制剂，可作为具有低微摩尔抑制活性的探针分子。
产品描述

ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization and acts as a probe molecule that has low micromolar inhibitory activity.
体外实验

Western Blot Analysis Cell Line:HEK293T cells Concentration:0-40 μM in the presence or absence of 20 μM 5-Furd Incubation Time:16 hours Result:Inhibited the increased ATAD5 protein levels induced by 5-Furd.
体内实验

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同义词

——
通路

Others
靶点

Other Targets
受体

ATAD5
研究领域

——
适应症

——

CAS Number

381168-77-0
分子量

334.32
分子式

C19H12F2N4
纯度

>98% (HPLC)
溶解度

DMSO:120 mg/mL?(358.94 mM)
SMILES

Fc1ccc(Nc2nc(nc3ccccc23)-c2ccncc2)cc1F
化学全称

(S)-9b-(4-Chlorophenyl)-1-(34-difluorobenzoyl)-23-dihydro-1H-imidazo[21-a]isoindol-5(9bH)-one

1.Rohde JM et al. Discovery of ML367 inhibitor of ATAD5 stabilization. Probe Reports from the NIH Molecular Libraries Program.

计算器

产品手册

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