5-Methylcytosine ( —— )

产品货号. M20002 CAS No. 554-01-8

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产品名称

5-Methylcytosine
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本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

5-甲基胞嘧啶是真核 DNA 中发现的甲基化核苷酸碱基。在动物中，胞嘧啶 DNA 甲基化形成 5-甲基胞嘧啶主要存在于回文序列 CpG 中。在植物中，甲基化序列是CpNpGp，其中N可以是任何碱基。 5-甲基胞嘧啶是由 DNA 甲基转移酶作用形成的表观遗传修饰。
产品描述

5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. In animals the DNA methylation of cytosine to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In plants the methylated sequence is CpNpGp where N can be any base. 5-Methylcytosine is an epigenetic modification formed by the action of DNA methyltransferases. In bacteria 5-methylcytosine can be found at a variety of sites and is often used as a marker to protect DNA from being cut by native methylation-sensitive restriction enzymes.
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1.Pfeifer GP et al. Mutations induced by ultraviolet light. Mutat Res. 2005 Apr 1;571(1-2):19-31.

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