NADH disodium salt hydrate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

NADH 是烟酰胺腺嘌呤二核苷酸 (NAD) 的还原形式，可以作为还原反应的一部分贡献电子。在此过程中，NADH 被氧化产生 NAD+。多种酶使用 NADH 加 H+ 来还原底物，生成 NAD+ 以及还原产物。

NADH is the reduced form of nicotinamide adenine dinucleotide (NAD) that can donate electrons as part of a reducing reaction. In that process NADH becomes oxidized to produce NAD+. A variety of enzymes use NADH plus H+ to reduce substrates generating NAD+ as well as the reduced product.

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Animal Model:Male ICR mice Dosage:5 μmol/mouse Administration:Intraperitoneal injection or oral administration, once Result:Produced significant increases in urinary excretions of nicotinamide (Nam) with intraperitoneal injection. Oral administration did not produce any increases in Nam or its metabolites.Animal Model:Male C57BL/6J mice Dosage:500 mg/kg Administration:Intragastric administration, 15 min before ethanol administration Result:Significantly increased blood acetaldehyde levels in mice administered with alcohol between 30 min and two hours. Significantly reduced the acetaldehyde in the blood after two hours. Inhibited the decrease of NAD+/NADH redox ratio in hepatocytes.

Disodium NADH | NADH disodium salt

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Other Targets

Others

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606-68-8

709.4

C21H27N7Na2O14P2

>98% (HPLC)

DMSO:42.3 mM

[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O

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(-20℃)

With Ice Pack

≥ 2 years