Halofenozide

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Halofenozide 是一种蜕皮类固醇激动剂。

Halofenozide is an ecdysteroid agonist and used as a pesticide.

Halofenozide (RH-0345) reduces both growth and development of oocytes in vitro. Cell Viability Assay Cell Line:Cultured ovarieswere dissected from female adult beetles of mealworm, Tenebrio molitor (T. molitor)Concentration:1 μM and 10 μM Incubation Time:4 days Result:Did not cause a significant effect on ecdysteroid amounts in the culture medium using ovaries from 0- and 2-day-old females at 10 μM. Caused a small significant increase of the amounts of ovarian ecdysteroids in the culture medium at 1 μM in the culture medium and with 2-day-old ovaries.

After topical application of Halofenozide (RH-0345; 5 and 10 μg) on adult females, the highest dose (10 μg) reduces significantly the reproductive parameters scored: namely the oviposition period, the fecundity and the egg viability.Halofenozide at the two doses tested (5 and 10 μg) causes smaller eggs with a decrease in length, width and volume. Animal Model:Newly emerged (0-day-old) adult females of T. molitor Dosage:5 and 10 μg Administration:Topically applied Result:Caused smaller eggs with a decrease in length, width and volume at the two doses tested (5 and 10 μg) .

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112226-61-6

330.81

C18H19ClN2O2

>98% (HPLC)

DMSO:10 mM

CC(C)(C)N(NC(=O)c1ccc(Cl)cc1)C(=O)c1ccccc1

N'-benzoyl-N'-(tert-butyl)-4-chlorobenzohydrazide

(-20℃)

With Ice Pack

≥ 2 years