2'-Deoxyadenosine 5'-monophosphate
CAS No. 653-63-4
2'-Deoxyadenosine 5'-monophosphate ( D-AMP )
产品货号. M19653 CAS No. 653-63-4
腺苷是一种核苷,由通过 -N9-糖苷键连接到核糖(呋喃核糖)部分的腺嘌呤组成。单磷酸脱氧腺苷是常见核酸 ATP 或三磷酸腺苷的衍生物,其中核苷酸戊糖 2' 碳上的 -OH(羟基)基团已被除去(因此名称中的脱氧部分)。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 50MG | ¥139 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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| 1 mL x 10 mM in DMSO | ¥150 | 有现货 |
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生物学信息
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产品名称2'-Deoxyadenosine 5'-monophosphate
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述腺苷是一种核苷,由通过 -N9-糖苷键连接到核糖(呋喃核糖)部分的腺嘌呤组成。单磷酸脱氧腺苷是常见核酸 ATP 或三磷酸腺苷的衍生物,其中核苷酸戊糖 2' 碳上的 -OH(羟基)基团已被除去(因此名称中的脱氧部分)。
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产品描述Adenosine is a nucleoside comprised of adenine attached to a ribose (ribofuranose) moiety via a -N9-glycosidic bond. Deoxyadenosine monophosphate is a derivative of the common nucleic acid ATP or adenosine triphosphate in which the -OH (hydroxyl) group on the 2' carbon on the nucleotide's pentose has been removed (hence the deoxy- part of the name). Additionally the monophosphate of the name indicates that two of the phosphoryl groups of GTP have been removed most likely by hydrolysis. Deoxyadenosine monophosphate is abbreviated dAMP..
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体外实验2′-Deoxyadenosine 5′-monophosphate (dAMP) is incorporated into Caco-2 cells in a time-dependent manner. The uptake of 2′-Deoxyadenosine 5′-monophosphate is increased with a drop in pH, suggesting that 2′-Deoxyadenosine 5′-monophosphate transport activity might be linked to the protons. 2′-Deoxyadenosine 5′-monophosphate uptake by Caco-2 cells is pH- and Na+-dependent.
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体内实验——
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同义词D-AMP
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number653-63-4
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分子量331.22
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分子式C10H14N5O6P
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纯度>98% (HPLC)
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溶解度DMSO:10 mM
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SMILESNc1ncnc2n(cnc12)[C@H]1C[C@H](O)[C@@H](COP(O)(O)=O)O1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Hohenester E Hutchinson W L Pepys M B et al. Crystal structure of a decameric complex of human serum amyloid P component with bound dAMP[J]. Journal of Molecular Biology 1997 269(4):0-578.
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