L-Histidine monohydrochloride monohydrat

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

组氨酸（缩写为 His 或 H）是一种 α-氨基酸。 L-异构体是 22 种蛋白氨基酸之一，即蛋白质的组成部分。

Histidine (abbreviated as His or H) is an alpha-amino acid. The L-isomer is one of the 22 proteinogenic amino acids i.e. the building blocks of proteins. It is classified as a charged polar because of the hydrophilic nature of the imidazole side chain. L-Histidine is a positively charged (pKa 6.5) aromatic amino acid. Histidine residues are often found in enzyme active sites where the chemistry of the imidazole ring of histidine makes it a nucleophile and a good acid/base catalyzer. Histidine is special in that its biosynthesis is inherently linked to the pathways of nucleotide formation. In the first step of histidine synthesis PRPP (5-phosphoribosyl-alpha-pyrophosphate) condenses with ATP to form a purine N1-5'-phosphoribosyl ATP in a reaction that is driven by the subsequent hydrolysis of the pyrophosphate that condenses out. Glutamine plays a role as an amino group donor resulting in the formation of 5-aminoamidazole-4-carboximide ribonucleotide (ACAIR) which is an intermediate in purine biosynthesis. Hisitidne is catabolized by the enzyme histidine ammonia-lyase which converts histidine into ammonia and urocanic acid.

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Others

Other Targets

Others

Others

accessory substance

5934-29-2

209.63

C6H12ClN3O3

>98% (HPLC)

DMSO:10 mM

O.Cl.N[C@@H](Cc1cnc[nH]1)C(O)=O

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(-20℃)

With Ice Pack

≥ 2 years