PATULIN

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

棒曲霉素是一种霉菌毒素，由腐烂苹果中常见的多种霉菌产生，包括曲霉菌和青霉菌。

Patulin is a mycotoxin produced by a variety of molds commonly found in rotting apples including Aspergillus and Penicillium.

Apoptosis Analysis Cell Line:HepG2 cells Concentration:2 μM Incubation Time:6-24 h Result:Increased the levels of active cleaved caspase-3 at 12 or 24 h.Western Blot Analysis Cell Line:HepG2 cells Concentration:2 μM Incubation Time:3-24 h Result:Increases the LC3-II levels.Immunofluorescence Cell Line:HepG2 cells Concentration:2 μM Incubation Time:6-24 h Result:Increased the numbers of swollen mitochondria with scarce or disordered cristae.

Animal Model:Male CF-1 mice Dosage:1-3.75 mg/kg Administration:i.p., once time Result:Increased the damage index and TBARS production in the brain, liver and kidneys of mice in a dose-dependently manner (2.5-3.75 mg/kg).Reduced the concentration of the reduced form of intracellular glutathione in the brain, liver and kidneys of mice at a dose of 2.5-3.75 mg/kg.Decreased the levels of GSH.Increased lipid peroxidation.

Clavacin | Expansin | Claviform

Others

Other Targets

Others

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149-29-1

154.12

C7H6O4

>98% (HPLC)

Ethanol:<1 mg/mL;DMSO:<1 mg/mL;Water:100 mg/mL (127.77 mM)

C1C=C2C(=CC(=O)O2)C(O1)O

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(-20℃)

With Ice Pack

≥ 2 years