kuwanon G

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Kuwanon G 作为 PTP1B 和 α-葡萄糖苷酶的双重抑制剂以及胰岛素增敏剂，有可能被用作 II 型糖尿病的有效治疗方法。

Kuwanon G as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for Type II diabetes mellitus. Kuwanon G has anti-inflammatory activity, it can attenuate atherosclerosis through inhibiting foam cell formation and inflammatory response. Kuwanon G is a potent inhibitor of Mycobacterium tuberculosis protein tyrosine phosphatase B. Kuwanon G shows acetylcholinesterase (AChE) and butyrylcholinesterase(BChE) inhibitory activities, it may be a promising candidate for preventive and therapeutic agents for Alzheimer's disease. Kuwanon G prevents the pathological progression of allergic asthma through the inhibition of lung destruction by inflammation and immune stimulation. Kuwanon G has antibacterial activity against oral pathogens. Kuwanon G is a specific antagonist for the GRP-preferring receptor and can be useful for studying the physiological and pathological role of GRP.

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Others

Other Targets

α-glucosidase|PTP1B|AChE|BChE

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75629-19-5

692.7

C40H36O11

>98% (HPLC)

In Vitro:?DMSO : 50 mg/mL (72.18 mM)

CC1=CC(C(C(C1)C2=C(C=C(C=C2)O)O)C(=O)C3=C(C=C(C=C3)O)O)C4=C(C=C(C5=C4OC(=C(C5=O)CC=C(C)C)C6=C(C=C(C=C6)

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(-20℃)

With Ice Pack

≥ 2 years