Feruloyltyramine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

NTF很可能抑制COX酶，从而抑制血小板上P-选择素的表达，是一种血小板聚集抑制剂。

N-trans-Feruloyltyramine(NTF) has hepatoprotective effect. NTF has antioxidative activity against Aβ(1-42)-induced neuronal death. NTF is likely to inhibit COX enzymes, thereby suppressing P-selectin expression on platelets, is a platelet aggregation inhibitor. NTF inhibits melanogenesis in a dose-dependent manner, NTF induces downregulation of tyrosinase resulted in suppression of melanin biosynthesis in murine B16 melanoma cells.

Cell Viability Assay Cell Line:SK-N-SH cells Concentration:10, 25, 50, 100, 150, 250, 500 μM Incubation Time:For 3 hours prior H2O2Result:Protected the cells against H2O2 (150 μM)-induced toxicity as determined by a significant higher percentage of viability in cells.Western Blot Analysis Cell Line:SK-N-SH cells Concentration:25, 50, 100 μM Incubation Time:For 3 hours prior H2O2 Result:Abolished H2O2-induced Bax expression. Significantly decreased activated caspase-3 levels.

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Microbiology/Virology

HIV

Others

Others-Field

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66648-43-9

313.35

C18H19NO4

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (319.13 mM)

COC1=C(C=CC(=C1)C=CC(=O)NCCC2=CC=C(C=C2)O)O

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(-20℃)

With Ice Pack

≥ 2 years