Ursonic Acid ( 3-Ketoursolic acid )

产品货号. M18918 CAS No. 6246-46-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

产品询价大包装询价加入购物车

产品名称

Ursonic Acid
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

熊果酸属于熊果烷三萜家族，其结构基于五环熊果烷骨架。它具有作为 HIV-1 蛋白酶抑制剂的潜力。
产品描述

Ursonic acid belongs to the family of Ursane Triterpenes whose structure is based on the pentacyclic ursane skeleton. It has potential as HIV-1 Protease Inhibitor.
体外实验

Cell Proliferation Assay Cell Line:T24 human bladder cancer cells Concentration:12.5-50 μM Incubation Time:48 h Result:Inhibited cell proliferation in a dose-dependent manner.Western Blot Analysis Cell Line:T24 human bladder cancer cells Concentration:12.5-50 μM Incubation Time:48 h Result:Inhibited the anti-apoptotic signaling (pAkt1, pIκBα, NF-κBp65 and Bcl-2).
体内实验

Animal Model:Adult male albino ratsDosage:5-20 mg/kg Administration:p.o., twice a day, 30 days Result:Increased weight gain and food intake.Decreased AST and ALT activities and total and indirect bilirubin levels.Increased direct bilirubin and levels of non-enzymic antioxidants (GSH, ascorbic acid and a-tocopherol).Decreased lipid peroxidation.
同义词

3-Ketoursolic acid
通路

Others
靶点

Other Targets
受体

Others
研究领域

Others-Field
适应症

——

CAS Number

6246-46-4
分子量

454.69
分子式

C30H46O3
纯度

>98% (HPLC)
溶解度

DMSO : 10 mg/mL 21.99 mM;
SMILES

[C@H]1(CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]3[C@@]4(CCC(=O)C3(C)C)C)C)[C@@H]2[C@H]1C)C)C(=O)O)C
化学全称

——

1. Yanuar A, et al. Bioinformation. 2014 Feb 19;10(2):52-5.

计算器

产品手册

关联产品

Sodium Hydrogen Sulf...

Sodium Hydrogen Sulfide (hydrate) is, like nitric oxide, an important gaseous mediator that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. Sodium Hydrogen Sulfide (hydrate) is an H2S donor commonly used in cellular and whole animal experimental systems. For example, it has been used to suggest that H2S promotes neutrophil migration, reduces airway inflammation, and protects neurites, heart, and intestine from chemical or ischemic-reperfusion damage.
Ac-MBP 1-11

Ac-MBP 1-11, a short peptide sequence, is the major encephalitogenic epitope in myelin basic protein (MBP).
AMRI-59

AMRI-59 是一种有效的 PrxI 抑制剂，具有抗肿瘤活性。