Ursonic Acid ( 3-Ketoursolic acid )

产品货号. M18918 CAS No. 6246-46-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

产品询价大包装询价加入购物车

产品名称

Ursonic Acid
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

熊果酸属于熊果烷三萜家族，其结构基于五环熊果烷骨架。它具有作为 HIV-1 蛋白酶抑制剂的潜力。
产品描述

Ursonic acid belongs to the family of Ursane Triterpenes whose structure is based on the pentacyclic ursane skeleton. It has potential as HIV-1 Protease Inhibitor.
体外实验

Cell Proliferation Assay Cell Line:T24 human bladder cancer cells Concentration:12.5-50 μM Incubation Time:48 h Result:Inhibited cell proliferation in a dose-dependent manner.Western Blot Analysis Cell Line:T24 human bladder cancer cells Concentration:12.5-50 μM Incubation Time:48 h Result:Inhibited the anti-apoptotic signaling (pAkt1, pIκBα, NF-κBp65 and Bcl-2).
体内实验

Animal Model:Adult male albino ratsDosage:5-20 mg/kg Administration:p.o., twice a day, 30 days Result:Increased weight gain and food intake.Decreased AST and ALT activities and total and indirect bilirubin levels.Increased direct bilirubin and levels of non-enzymic antioxidants (GSH, ascorbic acid and a-tocopherol).Decreased lipid peroxidation.
同义词

3-Ketoursolic acid
通路

Others
靶点

Other Targets
受体

Others
研究领域

Others-Field
适应症

——

CAS Number

6246-46-4
分子量

454.69
分子式

C30H46O3
纯度

>98% (HPLC)
溶解度

DMSO : 10 mg/mL 21.99 mM;
SMILES

[C@H]1(CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]3[C@@]4(CCC(=O)C3(C)C)C)C)[C@@H]2[C@H]1C)C)C(=O)O)C
化学全称

——

1. Yanuar A, et al. Bioinformation. 2014 Feb 19;10(2):52-5.

计算器

产品手册

关联产品

L-Asparaginase

一种有效非选择性黑素皮质激素受体 (MCR) 激动剂。Melanotan I 是一种合成的 α- 黑素细胞刺激激素 (α-MSH) 的类似物，刺激黑色素生成。Melanotan I 可以通过模仿 α-MSH 对黑素细胞的黑素皮质素 1 型受体 (MC1R) 的作用来诱导皮肤晒黑。Melanotan I 可以用于阳光诱发皮肤癌、黑色素瘤、炎症和男性勃起功能障碍等研究。
Cyanidin3-glucopyran...

Cyanidin3-glucopyranosyl-(1→6)-[3-xylopyranosyl-(1→2)]-galactopyranoside
Glicoricone

Glicoricone acts as a partial estrogen antagonist. Glicoricone inhibited the monoamine oxidase with the IC50 values of 6.0 x 10(-5)-1.4 x 10(-4) M.