Isoliquiritin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

异甘草苷、甘草苷和异甘草苷可抑制 p53 依赖性途径并显示 Akt 活性之间的串扰。

Isoliquiritin has antitussive effects. Isoliquiritin has antidepressant-like effects. Isoliquiritin, liquiritin and isoliquirigenin inhibits the p53-dependent pathway and shows crosstalk between Akt activities.

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Animal Model:Mice in Forced Swimming Test (FST) and the Tail Suspension Test (TST)Dosage:10, 20 and 40 mg/kg Administration:oral gavage Result:Reduced the immobility time in the FST and TST in mice.Increased 5-HT and NE level and Reduced the ratio of 5-HIAA/5-HT in the hippocampus, hypothalamus and cortex.

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Others

Other Targets

p53

Others-Field

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5041-81-6

418.39

C21H22O9

>98% (HPLC)

In Vitro:?DMSO : 125 mg/mL (298.76 mM)

C1=CC(=CC=C1C=CC(=O)C2=C(C=C(C=C2)O)O)OC3C(C(C(C(O3)CO)O)O)O

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(-20℃)

With Ice Pack

≥ 2 years