• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

Silychristin

CAS No. 33889-69-9

Silychristin ( —— )

产品货号. M18438 CAS No. 33889-69-9

水飞蓟汀是一种植物生长调节剂。 Silychristin 是一种抗肝毒性化合物。水飞蓟汀是辣根过氧化物酶和脂氧合酶的抑制剂。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1482 有现货
10MG ¥2242 有现货
25MG ¥3562 有现货
50MG ¥5087 有现货
100MG ¥6705 有现货
200MG ¥8865 有现货
500MG 获取报价 有现货
1G 获取报价 有现货
1 mL x 10 mM in DMSO ¥1577 有现货

生物学信息

  • 产品名称
    Silychristin
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    水飞蓟汀是一种植物生长调节剂。 Silychristin 是一种抗肝毒性化合物。水飞蓟汀是辣根过氧化物酶和脂氧合酶的抑制剂。
  • 产品描述
    Silychristin is a plant growth regulator. Silychristin is an anti-hepatotoxic agent. Silychristin is the inhibitor of horseradish peroxidases and lipoxygenase.
  • 体外实验
    Silychristin exhibits a strong inhibition of MCT8-mediated T3 uptake with an IC50 of 110 nM in MCT8 overexpressing MDCK1-cells.Silychristin causes no cytotoxic for fibroblasts.Silychristin (6.5-75 μM; 24 hours) diminishes UVA toxicity and reduces ROS generation, and the protective effect is dose-dependent.Silychristin (12.5μM, 25μM) reduces the metalloproteinase-1 (MMP-1) level in cells. Cell Viability Assay Cell Line:NHDF Concentration: 6.5 μM,12.5 μM,25 μM,50 μM,75 μM Incubation Time:24 hours Result:Diminished UVA toxicity and reduced ROS generation in dose-dependent.Cell Viability Assay Cell Line:NHDF Concentration:12.5 μM, 25 μM Incubation Time: Result:Reduced the metalloproteinase-1 (MMP-1) level in cells.
  • 体内实验
    ——
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    5-Lipoxygenase
  • 研究领域
    Others-Field
  • 适应症
    ——

化学信息

  • CAS Number
    33889-69-9
  • 分子量
    482.44
  • 分子式
    C25H22O10
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?DMSO : 100 mg/mL (207.28 mM)
  • SMILES
    COc1cc(ccc1O)[C@@H]1Oc2c(cc(cc2O)[C@H]2Oc3cc(O)cc(O)c3C(=O)[C@@H]2O)[C@H]1CO
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Vav?íková E, et al. Regioselective Alcoholysis of Silychristin Acetates Catalyzed by Lipases[J]. International Journal of Molecular Sciences, 2015, 16(6):11983-11995.
产品手册
关联产品
  • EZH2-IN-15

    EZH2-IN-15 (SHR2554) 是一个 EZH2 抑制剂。EZH2-IN-15 具有抗肿瘤活性,可用于 H3K27me3 依赖性肿瘤的研究。

  • 2-heptyl-3-hydroxy-4...

    2-heptyl-3-hydroxy-4(1H)-Quinolone (Pseudomonas Quinolone Signal) is a quorum-sensing signalling molecule produced by Pseudomonas aeruginosa in response to increased cell density. It increases the expression of the lasB gene in P. aeruginosa, the secretion of the metabolites pyocyanin and the lectin PA-IL, as well as increasing biofilm production in P. aeruginosa populations. It also reduces the iron content of the P. aeruginosa growth medium when used at a concentration of 40 μM and acts as an iron chelator in iron sulphate solutions.

  • MLS000532223

    MLS000532223 是一种选择性 Rho 家族 GTPases 抑制剂(EC50:16 μM 至 120 μM)。