Silychristin
CAS No. 33889-69-9
Silychristin ( —— )
产品货号. M18438 CAS No. 33889-69-9
水飞蓟汀是一种植物生长调节剂。 Silychristin 是一种抗肝毒性化合物。水飞蓟汀是辣根过氧化物酶和脂氧合酶的抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ¥1482 | 有现货 |
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| 10MG | ¥2242 | 有现货 |
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| 25MG | ¥3562 | 有现货 |
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| 50MG | ¥5087 | 有现货 |
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| 100MG | ¥6705 | 有现货 |
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| 200MG | ¥8865 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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| 1 mL x 10 mM in DMSO | ¥1577 | 有现货 |
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生物学信息
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产品名称Silychristin
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述水飞蓟汀是一种植物生长调节剂。 Silychristin 是一种抗肝毒性化合物。水飞蓟汀是辣根过氧化物酶和脂氧合酶的抑制剂。
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产品描述Silychristin is a plant growth regulator. Silychristin is an anti-hepatotoxic agent. Silychristin is the inhibitor of horseradish peroxidases and lipoxygenase.
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体外实验Silychristin exhibits a strong inhibition of MCT8-mediated T3 uptake with an IC50 of 110 nM in MCT8 overexpressing MDCK1-cells.Silychristin causes no cytotoxic for fibroblasts.Silychristin (6.5-75 μM; 24 hours) diminishes UVA toxicity and reduces ROS generation, and the protective effect is dose-dependent.Silychristin (12.5μM, 25μM) reduces the metalloproteinase-1 (MMP-1) level in cells. Cell Viability Assay Cell Line:NHDF Concentration: 6.5 μM,12.5 μM,25 μM,50 μM,75 μM Incubation Time:24 hours Result:Diminished UVA toxicity and reduced ROS generation in dose-dependent.Cell Viability Assay Cell Line:NHDF Concentration:12.5 μM, 25 μM Incubation Time: Result:Reduced the metalloproteinase-1 (MMP-1) level in cells.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体5-Lipoxygenase
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研究领域Others-Field
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适应症——
化学信息
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CAS Number33889-69-9
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分子量482.44
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分子式C25H22O10
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (207.28 mM)
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SMILESCOc1cc(ccc1O)[C@@H]1Oc2c(cc(cc2O)[C@H]2Oc3cc(O)cc(O)c3C(=O)[C@@H]2O)[C@H]1CO
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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2-heptyl-3-hydroxy-4...
2-heptyl-3-hydroxy-4(1H)-Quinolone (Pseudomonas Quinolone Signal) is a quorum-sensing signalling molecule produced by Pseudomonas aeruginosa in response to increased cell density. It increases the expression of the lasB gene in P. aeruginosa, the secretion of the metabolites pyocyanin and the lectin PA-IL, as well as increasing biofilm production in P. aeruginosa populations. It also reduces the iron content of the P. aeruginosa growth medium when used at a concentration of 40 μM and acts as an iron chelator in iron sulphate solutions.
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MLS000532223
MLS000532223 是一种选择性 Rho 家族 GTPases 抑制剂(EC50:16 μM 至 120 μM)。
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