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Bisdemethoxycurcumin
CAS No. 24939-16-0
Bisdemethoxycurcumin ( Curcumin III, Bisdemethoxycurcumin )
产品货号. M18307 CAS No. 24939-16-0
双去甲氧基姜黄素 (BDMC) 是姜黄素的天然去甲氧基衍生物。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥235 | 有现货 |
|
| 10MG | ￥353 | 有现货 |
|
| 25MG | ￥641 | 有现货 |
|
| 50MG | ￥1014 | 有现货 |
|
| 100MG | ￥1467 | 有现货 |
|
| 500MG | ￥3564 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥258 | 有现货 |
|
生物学信息
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产品名称Bisdemethoxycurcumin
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述双去甲氧基姜黄素 (BDMC) 是姜黄素的天然去甲氧基衍生物。
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产品描述Bisdemethoxycurcumin (BDMC) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagocytosis, interacting with 1α, 25-dihydroxy vitamin D3 to stimulate amyloid-β clearance by macrophages (optimal stimulation at 100 nM BDMC) [1]. More stable than curcumin in physiological media, BDMC suppresses proliferation of cancer cells. It down-regulates the transcriptional coactivator p300, suppressing the Wnt/β-catenin pathway, and inhibits LPS induction of iNOS expression.
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体外实验——
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体内实验——
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同义词Curcumin III, Bisdemethoxycurcumin
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通路Others
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靶点Other Targets
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受体p300|Wnt/β-catenin
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研究领域Cancer
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适应症——
化学信息
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CAS Number24939-16-0
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分子量308.33
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分子式C19H16O4
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 66.67 mg/mL (216.23 mM)
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SMILESOc2ccc(/C=C/C(=O)CC(=O)/C=C/c1ccc(O)cc1)cc2
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化学全称(1E,6E)-1,7-Bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Fiala, M., Liu, P.T., Espinosa-Jeffrey, A., et al. Proceedings of the National Academy of Sciences of the United States of America 104(31), 12849-12854 (2007).
产品手册
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