Sinensetin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Sinensetin 是一种甲基化黄酮，存在于某些柑橘类水果中。 sinensetin 具有有效的抗血管生成和抗炎作用，可增强脂肪生成和脂肪分解。

Sinensetin is a methylated flavone found in certain citrus fruits. pocess potent antiangiogenesis and anti-inflammatory, sinensetin enhances adipogenesis and lipolysis.

Western Blot Analysis Cell Line:3T3-L1 Concentration:2, 10, 40 μM Incubation Time:24 d Result: Increased cellular lipid accumulation and triglyceride content in a dose-dependent manner.Increased the expression of PPARγ1, PPARγ2, C/EBPα, and aP2.Cell Proliferation Assay Cell Line:CCRF-CEM cell, Jurkat Concentration:6.25–100 μM Incubation Time:24 or 48 h Result:Inhibited cell viability with different concentrations of sinensetin for 24 h and 48 h.Apoptosis Analysis Cell Line:Jurkat cell Concentration:50 μM, 100 μM Incubation Time:24 h and 48 h Result:Induced a sub-G1 population and apoptotic.

Animal Model:Carrageenan-induced paw edema in male C57BL/6 mice Dosage:50 mg/kg, single dose Administration:Intraperitoneal injection (i.p.)Result:Sloewd the volume increased of the carrageenan-treated paw at 6 h.

Pedalitin permethyl ether

Others

Other Targets

hPGDS/Others

Others-Field

——

2306-27-6

372.37

C20H20O7

>98% (HPLC)

DMSO : 12.5 mg/mL 33.57 mM;

COc1ccc(cc1OC)C2=CC(=O)c3c(OC)c(OC)c(cc3O2)OC

——

(-20℃)

With Ice Pack

≥ 2 years