O-6-Deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl (3β)-3-[(4-O-β-D-glucopyranosyl-α-L- arabinopyranosyl)oxy]olean-12-en-28-oate

MRT-2359 是一种口服有效的 GSPT1 降解剂 (IC50: >30 nM 且 <300 nM) ，具有抗肿瘤活性。MRT-2359 还抑制耐药非小细胞肺癌 (NSCLC) 和小细胞肺癌 (SCLC) 细胞的生长。MRT-2359 在 MYC 驱动的细胞系中表现出优先活性，例如 N-和 L-MYC 高 NSCLC 和 SCLC 患者来源的异种移植物 (PDX)。

(Trp63,Trp64)?-?C3a(63-77) is a C3a synthetic analogue peptide, which exhibits Ca2+ stimulating efficacy in human neutrophils and hC3aR or mC3aR expressing RBL-2H3 cells with EC50 of 9.5, 2.0 and 0.8 nM, respectively.