Linrodostat

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

BMS-986205 是一种选择性吲哚胺 2, 3-双加氧酶 1 (IDO1) 抑制剂。

BMS-986205 is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor.(In Vitro):Linrodostat (0.01-100 μM; 72 hours; SKOV-3 and Jurkat clone E6-1 cells) treatment reduces the number of viable cells compared with the non-treated control. Linrodostat also induces cell death at much lower concentrations and its IC50 is 6.3 μM.

Linrodostat (0.01-100 μM; 72 hours; SKOV-3 and Jurkat clone E6-1 cells) treatment reduces the number of viable cells compared with the non-treated control. Linrodostat also induces cell death at much lower concentrations and its IC50 is 6.3 μM. Cell Viability Assay Cell Line:SKOV-3 and Jurkat clone E6-1 cells Concentration:0.01-100 μM Incubation Time:72 hours Result:Reduced the number of viable cells compared with the non-treated control and induced cell death at much lower concentrations.

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BMS-986205 | ONO-7701

Others

Other Targets

IDO1

Cancer

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1923833-60-6

410.91

C24H24ClFN2O

>98% (HPLC)

DMSO : 50 mg/mL 121.68 mM; H2O : < 0.1 mg/mL

Clc1ccc(cc1)NC(=O)[C@H](C)[C@@H]2CC[C@@H](CC2)c3ccnc4ccc(F)cc34

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(-20℃)

With Ice Pack

≥ 2 years