Asperuloside ( —— )

产品货号. M18011 CAS No. 14259-45-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Asperuloside
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Asperuloside 是一种环烯醚萜，来源于蛇舌草，具有抗炎活性。Asperuloside 可抑制诱导型一氧化氮合酶 (iNOS)，抑制 NF-κB 和 MAPK 信号通路。
产品描述

Asperuloside has anti-inflammatory activity.
体外实验

Western Blot Analysis Cell Line:U937 cells Concentration:0-5 mM Incubation Time:24 h Result:Increased the cleaved Caspase-3, Caspase-9, and PARP, and Cyto-c release from mitochondria.Induced expression of GRP78, p-PERK, p-eIF2α, CHOP, p-IRE1, XBP1, ATF6 and cleaved Caspase-12
体内实验

Animal Model:Rats consuming a high fat diet (HFD)Dosage:3 mg/day Administration:p.o., 0.3% in diet, daily, 12 weeks Result:Reduced body weight, energy intake, adiposity, blood glucose, and plasma insulin.
同义词

——
通路

Others
靶点

Other Targets
受体

Others
研究领域

——
适应症

——

CAS Number

14259-45-1
分子量

414.36
分子式

C18H22O11
纯度

>98% (HPLC)
溶解度

In Vitro:?DMSO : 100 mg/mL (241.34 mM)
SMILES

C(=O)(C)OCC1=C[C@@H]2OC(=O)C3=CO[C@H]([C@H]1[C@H]23)O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO
化学全称

——

1. Fujikawa T,et al. J Nutr Sci. 2012 Sep 5;1:e10.

计算器

产品手册

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