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L-Glutamic acid monosodium salt
CAS No. 142-47-2
L-Glutamic acid monosodium salt ( Monosodium glutamate | Sodium glutamate | MSG )
产品货号. M18010 CAS No. 142-47-2
L-Glutamic Acid monosodium salt (Monosodium glutamate) 是 mGlu1 受体的激活剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | ￥300 | 有现货 |
|
| 500MG | ￥446 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称L-Glutamic acid monosodium salt
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述L-Glutamic Acid monosodium salt (Monosodium glutamate) 是 mGlu1 受体的激活剂。
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产品描述Monosodium glutamate is one of the FLAVORING AGENTS used to impart a meat-like flavor. Medically it has been used to reduce blood ammonia levels in ammoniacal azotemia, therapy of hepatic coma, in psychosis, and INTELLECTUAL DISABILITY.
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体外实验Cell Viability Assay Cell Line: SH-SY5Y, IMR-32, SK-N-BE(2)Concentration:2, 5, 10, 20 mM Incubation Time: 24 and 48 h Result:Reduced cell viability in a dose-dependent manner.
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体内实验Animal Model:Crv4 mice model Dosage:3g/kg Administration:s.c., single dose Result:Reduced the number of Brn-3a+ RGCs by >70%.In the absence of mGlu1 receptor, MSG-induced retinal damage is diminished.Animal Model:CPF-induced rat model Dosage:750 mg/kg Administration:i.p.Result:Reduced CPF-induced oxidative stress by increasing the level of GSH and activity of GSH-related enzymes.
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同义词Monosodium glutamate | Sodium glutamate | MSG
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通路Others
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靶点Other Targets
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受体mGluR1
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研究领域Others-Field
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适应症——
化学信息
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CAS Number142-47-2
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分子量169.11
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分子式C5H8NO4·Na
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纯度>98% (HPLC)
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溶解度H2O : ≥ 100 mg/mL; 591.33 mM
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SMILESC(CC(=O)O)[C@@H](C(=O)[O-])N.[Na+]
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化学全称sodium (S)-2-amino-4-carboxybutanoate
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Liberatore F, et al. Permissive role for mglu1 metabotropic glutamate receptors in excitotoxic retinal degeneration. Neuroscience. 2017 Sep 14. pii: S0306-4522(17)30640-1.
产品手册
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