Vanillylacetone ( Zingerone | AI3-31837 | Gingerone )

产品货号. M17890 CAS No. 122-48-5

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产品名称

Vanillylacetone
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

香兰基丙酮在香料油和香水中用作香料添加剂，以引入辛辣香气，其化学结构与香兰素和丁子香酚等香料化学物质相似。
产品描述

Zingerone is absent in fresh ginger but cooking or heating transforms gingerol to zingerone. The compound has potent anti-inflammatory, antidiabetic, antilipolytic, antidiarrheal, and antispasmodic properties. It behaves as appetite stimulant, anxiolytic, antithrombotic, radiation protective, and antimicrobial. Also, it inhibits the reactive nitrogen species important in causing Alzheimer's disease and many other disorders.
体外实验

Zingerone is a nontoxic methoxyphenol with potent anti-inflammatory, antidiabetic, antilipolytic, antidiarrhoeic, antispasmodic properties.Zingerone (0-2 mM) decreases neruoblastoma cell survival.Zingerone (0-2 mM) reduces cyclin D1 expression, increases cleavage of caspase-3 and PARP-1 in BE(2)-M17 cells.
体内实验

Zingerone (50, 100 ?mg/kg, p.o. daily for 21?days) protects against alloxan-induced diabetes via alleviation of oxidative stress and inflammation in rat.Zingerone (10 mg/kg, i.p.) inhibits tumor progression through mitotic arrest, failure of cell division, and stimulation of apoptosis.
同义词

Zingerone | AI3-31837 | Gingerone
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研究领域

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适应症

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1. Chen JC, et al. J Agric Food Chem, 2007, 55(21), 8390-8397.

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