Dolasetron

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Dolasetron (MDL-73147) 是一种血清素 5-HT3 受体拮抗剂，用于治疗化疗后的恶心和呕吐。

Dolasetron is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much antiemetic effect when symptoms are due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors.

——

——

HSDB 7565 | HSDB7565 | Dolasetron | Dolasetronum

Others

Other Targets

5-HT3

Others-Field

——

115956-12-2

324.38

C19H20N2O3

>98% (HPLC)

DMSO : ≥ 300 mg/mL; 924.87 mM

[H][C@]12C[C@@H](C[C@@H]3C[C@H](C1)C(=O)CN23)OC(=O)c1c[nH]c2ccccc12

(6R)-3-oxooctahydro-1H-2,6-methanoquinolizin-8-yl 1H-indole-3-carboxylate

(-20℃)

With Ice Pack

≥ 2 years