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Esonarimod
CAS No. 101973-77-7
Esonarimod ( Esonarimod | KE-298 | KE298 )
产品货号. M17753 CAS No. 101973-77-7
艾索那莫德是一种抗风湿药。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥103 | 有现货 |
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| 5MG | ￥164 | 有现货 |
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| 10MG | ￥231 | 有现货 |
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| 25MG | ￥453 | 有现货 |
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| 50MG | ￥728 | 有现货 |
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| 100MG | ￥1107 | 有现货 |
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| 200MG | ￥1647 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥181 | 有现货 |
|
生物学信息
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产品名称Esonarimod
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述艾索那莫德是一种抗风湿药。
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产品描述Esonarimod is an antirheumatic drug, suppressing lymphocyte activating factor activity or biosynthesis.(In Vitro):Esonarimod (KE-298) (10 to 300 μg/mL) suppresses the production of NO by RAW264.7 cells in a dose dependent manner. The IC50 of Esonarimod is 117.5 μg/mL. Esonarimod does not affect cellular viability at these tested doses. Esonarimod has no direct effect on NOS activity in cell-free extracts of RAW264.7 cells.(In Vivo):After repeated oral administration of Esonarimod (14C-KE-298), the radioactivity decreases rapidly and no tendency towards accumulation is found.
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体外实验——
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体内实验——
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同义词Esonarimod | KE-298 | KE298
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通路Others
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靶点Other Targets
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受体IL-1
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研究领域——
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适应症——
化学信息
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CAS Number101973-77-7
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分子量280.34
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分子式C14H16O4S
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纯度>98% (HPLC)
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溶解度——
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SMILESCC1=CC=C(C=C1)C(=O)CC(CSC(=O)C)C(=O)O
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化学全称Benzenebutanoic acid, alpha-((acetylthio)methyl)-4-methyl-gamma-oxo-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Inoue T, et al. KE-298 and its active metabolite KE-758 suppress nitric oxide production by murine macrophage cells and peritoneal cells from rats with adjuvant induced arthritis. J Rheumatol. 2001 Jun;28(6):1229-37.
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