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Potassium canrenoate
CAS No. 2181-04-6
Potassium canrenoate ( Canrenoate potassium | SC 14266 | SC-14266 )
产品货号. M17721 CAS No. 2181-04-6
Potassium canrenoate 是一种合成的孕二烯衍生物，具有抗醛固酮活性。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 50MG | ￥92 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Potassium canrenoate
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Potassium canrenoate 是一种合成的孕二烯衍生物，具有抗醛固酮活性。
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产品描述Canrenoate potassium is a synthetic pregnadiene derivative with anti-aldosterone activity.(In Vivo):Potassium canrenoate has been shown to cause in rats a dose-dependent increase in myelogenous leukemia and statistically significant increases in malignant tumor of the liver, thyroid, brain and mammary gland.Potassium canrenoate (20 mg/kg/day; drinking water) reduces isoprenaline-induced cardiac fibrosis in the rat.
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体外实验——
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体内实验Potassium canrenoate has been shown to cause in rats a dose-dependent increase in myelogenous leukemia and statistically significant increases in malignant tumor of the liver, thyroid, brain and mammary gland.Potassium canrenoate (20 mg/kg/day; drinking water) reduces isoprenaline-induced cardiac fibrosis in the rat.
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同义词Canrenoate potassium | SC 14266 | SC-14266
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通路GPCR/G Protein
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靶点S1P Receptor
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受体Mineralocorticoid Receptor
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研究领域Endocrinology
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适应症——
化学信息
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CAS Number2181-04-6
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分子量396.56
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分子式C22H29KO4
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纯度>98% (HPLC)
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溶解度In Vitro:?H2O : 100 mg/mL (252.17 mM)
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SMILES[K+].C(=O)(CC[C@@]1(CC[C@H]2[C@@H]3C=CC4=CC(=O)CC[C@@]4([C@H]3CC[C@]12C)C)O)[O-]
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化学全称17-alpha-Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, monopotassium salt
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Alexandre J, et al. J Cardiovasc Pharmacol Ther. 2015 May;20(3):313-21.
