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Veratric acid

CAS No. 93-07-2

Veratric acid ( 3,4-Dimethoxybenzoic acid )

产品货号. M17718 CAS No. 93-07-2

藜芦酸在生产抗生素和各种染料方面发挥着重要作用。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
500MG 获取报价 有现货
1G 获取报价 有现货
1 mL x 10 mM in DMSO ¥152 有现货

生物学信息

  • 产品名称
    Veratric acid
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    藜芦酸在生产抗生素和各种染料方面发挥着重要作用。
  • 产品描述
    Veratric acid plays an important role in producing antibiotics and various dyes. They are used as intermediates for pharmaceuticals (especially for antipyretic analgesic, anti-rheumatism) and other organic syntheses. It is used as a matrix for ionization of peptides, proteins, and carbohydrates.(In Vitro):Veratric acid (100, 200 μM) suppresses iNOS expression in LPS-stimulated RAW264.7 cells. Veratric acid (200 μM) inhibits LPS-induced activation of the PI3K/Akt pathway, HAT activation and HDAC3 expression in RAW264.7 cells.Veratric Acid (10-100 μg/mL) has anti-inflammatory activity, protects HaCaT cells against UVB-mediated phototoxicity, increases S-phase cells, and prevents UVB-mediated apoptosis.Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation.(In Vivo):Veratric acid (40 mg/kg, p.o., b.w.) significantly promotes ventricular function, reduces lipid peroxidation and increases antioxidants in l-NAME-induced hypertensive rats.
  • 体外实验
    Veratric acid (100, 200 μM) suppresses iNOS expression in LPS-stimulated RAW264.7 cells. Veratric acid (200 μM) inhibits LPS-induced activation of the PI3K/Akt pathway, HAT activation and HDAC3 expression in RAW264.7 cells.Veratric Acid (10-100 μg/mL) has anti-inflammatory activity, protects HaCaT cells against UVB-mediated phototoxicity, increases S-phase cells, and prevents UVB-mediated apoptosis. Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation.
  • 体内实验
    Veratric acid (40 mg/kg, p.o., b.w.) significantly promotes ventricular function, reduces lipid peroxidation and increases antioxidants in l-NAME-induced hypertensive rats.
  • 同义词
    3,4-Dimethoxybenzoic acid
  • 通路
    Angiogenesis
  • 靶点
    VEGFR
  • 受体
    Others
  • 研究领域
    Others-Field
  • 适应症
    ——

化学信息

  • CAS Number
    93-07-2
  • 分子量
    182.17
  • 分子式
    C9H10O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?DMSO : 100 mg/mL (548.94 mM)
  • SMILES
    COc1c(cc(cc1)C(=O)O)OC
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Lee KE, et al. Arch Dermatol Res. 2016 Apr;308(3):183-92.
产品手册
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