Veratric acid
CAS No. 93-07-2
Veratric acid ( 3,4-Dimethoxybenzoic acid )
产品货号. M17718 CAS No. 93-07-2
藜芦酸在生产抗生素和各种染料方面发挥着重要作用。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ¥152 | 有现货 |
|
生物学信息
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产品名称Veratric acid
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述藜芦酸在生产抗生素和各种染料方面发挥着重要作用。
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产品描述Veratric acid plays an important role in producing antibiotics and various dyes. They are used as intermediates for pharmaceuticals (especially for antipyretic analgesic, anti-rheumatism) and other organic syntheses. It is used as a matrix for ionization of peptides, proteins, and carbohydrates.(In Vitro):Veratric acid (100, 200 μM) suppresses iNOS expression in LPS-stimulated RAW264.7 cells. Veratric acid (200 μM) inhibits LPS-induced activation of the PI3K/Akt pathway, HAT activation and HDAC3 expression in RAW264.7 cells.Veratric Acid (10-100 μg/mL) has anti-inflammatory activity, protects HaCaT cells against UVB-mediated phototoxicity, increases S-phase cells, and prevents UVB-mediated apoptosis.Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation.(In Vivo):Veratric acid (40 mg/kg, p.o., b.w.) significantly promotes ventricular function, reduces lipid peroxidation and increases antioxidants in l-NAME-induced hypertensive rats.
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体外实验Veratric acid (100, 200 μM) suppresses iNOS expression in LPS-stimulated RAW264.7 cells. Veratric acid (200 μM) inhibits LPS-induced activation of the PI3K/Akt pathway, HAT activation and HDAC3 expression in RAW264.7 cells.Veratric Acid (10-100 μg/mL) has anti-inflammatory activity, protects HaCaT cells against UVB-mediated phototoxicity, increases S-phase cells, and prevents UVB-mediated apoptosis. Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation.
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体内实验Veratric acid (40 mg/kg, p.o., b.w.) significantly promotes ventricular function, reduces lipid peroxidation and increases antioxidants in l-NAME-induced hypertensive rats.
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同义词3,4-Dimethoxybenzoic acid
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通路Angiogenesis
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靶点VEGFR
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受体Others
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研究领域Others-Field
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适应症——
化学信息
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CAS Number93-07-2
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分子量182.17
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分子式C9H10O4
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (548.94 mM)
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SMILESCOc1c(cc(cc1)C(=O)O)OC
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Lee KE, et al. Arch Dermatol Res. 2016 Apr;308(3):183-92.
产品手册
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