FPH2

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

FPH2 (BRD-9424) 是一种促进 iPS 衍生肝细胞分化的小分子。

FPH2 (BRD-9424) is a small molecule promoting differentiation of iPS-derived hepatocytes.

FPH2 induces functional proliferation of hepatocytes in vitro, and thus may be useful for expanding mature human primary hepatocytes. FPH1 and FPH2 can increase in hepatocyte nuclei count and/or elevate the number of nuclei undergoing mitosis during primary screening, and these effects on hepatocytes are concentration dependent. Cells treated with FPH1 and FPH2 also maintain their liver-specific functions. Over 7 days, FPH2 induces hepatocyte doublings at a rate that is consistent with reported liver regeneration kinetics in vivo.

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BRD-9424

MAPK/ERK Signaling

p38 MAPK

Others

Others-Field

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957485-64-2

353.83

C14H16ClN5O2S

>98% (HPLC)

DMSO : ≥ 125 mg/mL; 353.28 mM

Clc1cc(NC(=S)Nc2cn(nc2C(=O)N)CC)c(OC)cc1

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(-20℃)

With Ice Pack

≥ 2 years