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Orexin 2 Receptor Agonist
CAS No. 1796565-52-0
Orexin 2 Receptor Agonist ( MDK-5220 | MDK5220. Orexin2 receptor agonist )
产品货号. M17380 CAS No. 1796565-52-0
Orexin 2 Receptor Agonist 是一种有效 (EC50: 23 nM) 和 OX2R 选择性（OX1R/OX2R EC50 比率：70）激动剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥523 | 有现货 |
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| 10MG | ￥695 | 有现货 |
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| 25MG | ￥1097 | 有现货 |
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| 50MG | ￥1655 | 有现货 |
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| 100MG | ￥2412 | 有现货 |
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| 200MG | ￥3447 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥698 | 有现货 |
|
生物学信息
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产品名称Orexin 2 Receptor Agonist
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Orexin 2 Receptor Agonist 是一种有效 (EC50: 23 nM) 和 OX2R 选择性（OX1R/OX2R EC50 比率：70）激动剂。
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产品描述MDK-5220 is a potent ans selective Orexin2 receptor agonist. MDK-5220 has CAS#1796565-52-0, which has previously no designed code name. For the convenience of communication, MedKoo temporally names it as MDK-5220 (note: 5220 is the last four digit of its CAS#). MDK-5220 was reported in WO2015088000. MDK-5220 exhibits an orexin agonist activity and is expected to be useful as an excellent therapeutic or preventive agent for narcolepsy.
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体外实验——
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体内实验——
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同义词MDK-5220 | MDK5220. Orexin2 receptor agonist
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通路Cell Cycle/DNA Damage
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靶点ROCK
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受体O2XR
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研究领域Neurological Disease
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适应症——
化学信息
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CAS Number1796565-52-0
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分子量586.7
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分子式C32H34N4O5S
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纯度>98% (HPLC)
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溶解度DMSO : ≥ 32 mg/mL; 54.54 mM
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SMILESc1(cccc(c1)C(=O)N(C)C)c1ccc(c(c1)S(=O)(=O)Nc1cccc(c1)NCCNC(=O)c1cc(ccc1)C)OC
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化学全称4'-methoxy-N,N-dimethyl-3'-(N-(3-((2-(3-methylbenzamido)ethyl)amino)phenyl)sulfamoyl)-[1,1'-biphenyl]-3-carboxamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Nagahara T, et al. J Med Chem. 2015 Oct 22;58(20):7931-7.
