Nampt-IN-1

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Nampt-IN-1 (LSN3154567) 是一种有效的选择性 NAMPT 抑制剂。 Nampt-IN-1 抑制纯化的 NAMPT，IC50 为 3.1 nM。

LSN3154567, also known as Nampt-IN-1, is a potent and elective NAMPT inhibitor. Nicotinamide phosphoribosyltransferase (NAMPT) is a promising antitumor target. NAMPT inhibition leads to attenuation of glycolysis, resulting in further perturbation of carbohydrate metabolism in cancer cells.

——

——

Nampt-IN-1 | Nampt-IN 1 | Nampt-IN1 | LSN3154567

Proteasome/Ubiquitin

Cysteine Protease

NAMPT|CSF-1R

Cancer

——

1698878-14-6

419.49

C20H25N3O5S

>98% (HPLC)

DMSO : ≥ 30 mg/mL; 71.52 mM

CC(C)(O)CS(=O)(=O)Nc1ccc2CN(CCc2c1)C(=O)COc3cccnc3

2-Hydroxy-2-methyl-N-[1,2,3,4-tetrahydro-2-[2-(3-pyridinyloxy)acetyl]-6-isoquinolinyl]-1-propanesulfonamide

(-20℃)

With Ice Pack

≥ 2 years