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NSC5844
CAS No. 140926-75-6
NSC5844 ( NSC5844 | NSC-5844 | NSC 5844 | RE640 )
产品货号. M17281 CAS No. 140926-75-6
NSC5844 (RE640) 是一种双喹啉化合物，具有 CC 趋化因子受体 1 型 (CCR1) 激动活性。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥449 | 有现货 |
|
| 5MG | ￥848 | 有现货 |
|
| 10MG | ￥1131 | 有现货 |
|
| 25MG | ￥1600 | 有现货 |
|
| 50MG | ￥2325 | 有现货 |
|
| 100MG | ￥3222 | 有现货 |
|
| 200MG | ￥4248 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称NSC5844
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述NSC5844 (RE640) 是一种双喹啉化合物，具有 CC 趋化因子受体 1 型 (CCR1) 激动活性。
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产品描述NSC5844, also known as RE640, is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic properties.
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体外实验NSC5844 (Compound 10) is a 4-aminoquinoline derivative, and has antitumor activity with GI50s of 7.35 ± 0.10 μM and 14.80 ± 0.35 μM against MDA-MB-468 and MCF-7 cells, respectively. NSC5844 (Compound 1) is cytotoxic to P. falciparum, inhibits the growth of chloroquine-sensitive (D-6) and -resistant (W-2) clones of P. falciparum, with IC50s of 17 and 27 nM, respectively.
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体内实验——
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同义词NSC5844 | NSC-5844 | NSC 5844 | RE640
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通路PI3K/Akt/mTOR signaling
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靶点PI3K
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受体CCR1
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研究领域Cancer
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适应症——
化学信息
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CAS Number140926-75-6
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分子量383.27
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分子式C20H16Cl2N4
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 1 mg/mL (2.61 mM)
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SMILESc1cc2c(ccnc2cc1Cl)NCCNc1c2ccc(cc2ncc1)Cl
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化学全称N,N'-bis(7-chloroquinolin-4-yl)ethane-1,2-diamine
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Zhang H, et al. Biomed PharmacOthers. 2008 Feb;62(2):65-9.
