lavendustin B

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Lavendustin B 是一种酪氨酸激酶抑制剂，也是一种 HIV-1 整合酶 (IN) 与其同源细胞辅助因子、晶状体上皮衍生生长因子 (LEDGF/p75) 相互作用的抑制剂。

Lavendustin B is a Tyrosine Kinase Inhibitor amd an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived growth factor (LEDGF/p75).

In HL-60 cells, Lavendustin B (0-1000 μM) inhibits the uptake of methylglucose, deoxyglucose, and dehydroascorbic acid in human erythrocytes in a dose-dependent manner, with 50% inhibition observed at approximately 10-30 μM. Moreover, increasing concentrations of Lavendustin B inhibited, in a dose-dependent manner, the binding of cytochalasin B to human erythrocyte membranes.

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Lavendustin B

Neuroscience

GluR

Tyrosine Kinase inhibitor| HIV-1 integrase

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125697-91-8

365.39

C21H19NO5

>98% (HPLC)

In Vitro:?DMSO : 50 mg/mL (136.84 mM)

O=C(O)c1cc(N(Cc2ccccc2O)Cc2ccccc2O)ccc1O

5-[Bis[(2-hydroxyphenyl)methyl]amino]-2-hydroxy-benzoic Acid

(-20℃)

With Ice Pack

≥ 2 years