MK-7288 ( MK7288 | MK 7288 )

产品货号. M16708 CAS No. 936626-07-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

MK-7288
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

一种新型组胺 H3 受体反向激动剂，用于治疗睡眠呼吸暂停综合征。
产品描述

A novel histamine H3 receptor inverse agonist for the treatment of sleep apnoea syndrome; significantly prolongs MWT sleep latency, and improves car driving simulation standard deviation of lane position in clinical trials.Sleep Disorder Phase 1 Clinical.
体外实验

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体内实验

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同义词

MK7288 | MK 7288
通路

GPCR/G Protein
靶点

Histamine Receptor
受体

Histamine Receptor
研究领域

Neurological Disease
适应症

Sleep Disorder

CAS Number

936626-07-2
分子量

401.507
分子式

C22H31N3O4
纯度

>98% (HPLC)
溶解度

——
SMILES

CN(CCN1CCCCC1)C(=O)C2CCC3(CC2)C4=C(C(=O)O3)N=C(C=C4)OC
化学全称

(1r,4r)-2'-methoxy-N-methyl-7'-oxo-N-(2-(piperidin-1-yl)ethyl)-7'H-spiro[cyclohexane-1,5'-furo[3,4-b]pyridine]-4-carboxamide

1. Sun H, et al. J Clin Pharmacol. 2013 Dec;53(12):1294-302.

计算器

产品手册

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