Bambuterol hydrochloride ( KWD-2183 )

产品货号. M16044 CAS No. 81732-46-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Bambuterol hydrochloride
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

一种长效 β-肾上腺素受体激动剂 (LABA)，用于治疗哮喘。
产品描述

A long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; also is a prodrug of terbutaline.Asthma Approved(In Vitro):Bambuterol ((±)-Bambuterol hydrochloride; KWD-2183 hydrochloride) is contraindicated in pregnancy and in people with seriously impaired liver function. It can be used by people with renal impairment, but dose adjustments are necessary. The adverse effect profile of bambuterol is similar to that of salbutamol, and may include fatigue, nausea, palpitations, headache, dizziness and tremor.
体外实验

Bambuterol ((±)-Bambuterol hydrochloride; KWD-2183 hydrochloride) is contraindicated in pregnancy and in people with seriously impaired liver function. It can be used by people with renal impairment, but dose adjustments are necessary. The adverse effect profile of bambuterol is similar to that of salbutamol, and may include fatigue, nausea, palpitations, headache, dizziness and tremor.
体内实验

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同义词

KWD-2183
通路

GPCR/G Protein
靶点

Adrenergic Receptor
受体

AChR|β-adrenergicreceptor
研究领域

Inflammation/Immunology
适应症

Asthma

CAS Number

81732-46-9
分子量

403.9009
分子式

C18H30ClN3O5
纯度

>98% (HPLC)
溶解度

DMSO: < 7.6 mg/mL
SMILES

CC(C)(C)NCC(C1=CC(=CC(=C1)OC(=O)N(C)C)OC(=O)N(C)C)O.Cl
化学全称

Carbamic acid, N,N-dimethyl-, 3-[[(dimethylamino)carbonyl]oxy]-5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]phenyl ester, hydrochloride (1:1)