Sulfamethoxazole

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

磺胺甲恶唑是一种磺酰胺类抑菌抗生素。

Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic. Target: Antibacterial Sulfonamides are structural analogs and competitive antagonists of para-aminobenzoic acid (PABA). (In Vitro):Sulfonamides are structural analogs and competitive antagonists of para-aminobenzoic acid (PABA). They inhibit normal bacterial utilization of PABA for the synthesis of folic acid, an important metabolite in DNA synthesis. The effects seen are usually bacteriostatic in nature. Folic acid is not synthesized in humans, but is instead a dietary requirement. This allows for the selective toxicity to bacterial cells (or any cell dependent on synthesizing folic acid) over human cells. Bacterial resistance to sulfamethoxazole is caused by mutations in the enzymes involved in folic acid synthesis that prevent the drug from binding to it.

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NSC 147832 | Ro 4-2130

Autophagy

Autophagy

DHPS| FolC

Infection

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723-46-6

253.28

C10H11N3O3S

>98% (HPLC)

Ethanol: 23 mg/mL (90.8 mM); DMSO: 51 mg/mL (201.35 mM)

CC1=CC(NS(=O)(C2=CC=C(N)C=C2)=O)=NO1

4-amino-N-(5-methylisoxazol-3-yl)benzenesulfonamide

(-20℃)

With Ice Pack

≥ 2 years