Dipivefrin hydrochloride ( Dipivefrin hydrochloride )

产品货号. M15433 CAS No. 64019-93-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Dipivefrin hydrochloride
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Dipivefrin hydrochloride (Dipivefrine hydrochloride) 是一种抗青光眼前体活性分子，通过角膜中的酯酶水解为其活性化合物肾上腺素。
产品描述

Dipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. It is available as ophthalmic solution (eye drops). (In Vivo):Dipivefrin hydrochloride (0.3-10 μg/kg; i.p.;) induces enhancement of memory involves central beta- but not alpha-adrenergic mechanisms.
体外实验

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体内实验

Dipivefrin hydrochloride (0.3-10 μg/kg; i.p.;) induces enhancement of memory involves central beta- but not alpha-adrenergic mechanisms. Animal Model:Male 60-day-old CFW mice (23-28 g)Dosage:0.3 μg/kg, 1.0 μg/kg, 3.0 μg/kg, 10 μg/kgAdministration:Intraperitoneal injection; post-training Result:Significantly enhanced retention of both inhibitory avoidance and Y-maze discrimination tasks in a dose-dependent manner.
同义词

Dipivefrin hydrochloride
通路

Endocrinology/Hormones
靶点

AChR
受体

AChR| Adrenergic Receptor
研究领域

——
适应症

——

CAS Number

64019-93-8
分子量

387.9
分子式

C19H27NO5·HCl
纯度

>98% (HPLC)
溶解度

DMSO: 10 mM
SMILES

CC(C)(C(Oc1c(OC(C(C)(C)C)=O)cc(C(O)CNC)cc1)=O)C.Cl
化学全称

(1)-4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-phenylene dipivalate hydrochloride

1.Nakamura M, et al. Ophthalmic Res. 1993;25(1):46-5

计算器

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