Schizandrin B

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Schisandrin B(Wuweizisu-B) 是从五味子中分离得到的二苯并环辛二烯衍生物。

Schisandrin B(Wuweizisu-B) is a dibenzocyclooctadiene derivative isolated from Fructus Schisandrae, has been shown to produce antioxidant effect on rodent liver and heart.

Real Time qPCR Cell Line:lymphocyte Concentration:10-50 μM Incubation Time:4 h Result:Increase in relative mRNA copy number of Nrf2, HO-1, TrxR1, and GCLC.Increased basal ROS levels and decreased GSH/GSSG ratio.

Animal Model:Mice endotoxic shock model Dosage:80 mg/kg.Administration:Intraperitoneally injected (i.p.), single dose.Result:Decreased proliferation and secretion of the proinflammatory cytokines IL-2, IL-6, and IFN-g .

Wuweizisu B

Cell Cycle/DNA Damage

ATM/ATR

ATR

Neurological Disease

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61281-37-6

400.46

C23H28O6

>98% (HPLC)

Ethanol: 10 mg/mL (24.97 mM); DMSO: 80 mg/mL (199.77 mM)

COC1=C(OC)C(OC)=C2C(CC(C)C(C)CC3=CC4=C(OCO4)C(OC)=C23)=C1

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(-20℃)

With Ice Pack

≥ 2 years